| Volatile agents |
| Anesthetic dose | Frontal θ-β activity | ↑ | Yes, >1.5 MAC |
| Increasing dose >1.5MAC | Diffuse θ-δ→burst suppression→silence | ↑→ 0 | |
| Nitrous oxide (alone) | Frontal fast oscillatory activity (>30 Hz) | ↑, especially with inspired concentration >50% | No |
| Propofol |
| Moderate dose | Frontal δ, waxing-waning α | ↑ | Yes, |
| Increasing high dose | Diffuse δ→burst suppression→silence | ↑↑→ 0 | with high doses |
| Barbiturates |
| Moderate dose | Frontal α frequency spindles | ↑ | Yes, |
| Increasing high dose | Diffuse δ→burst suppression→silence | ↑↑↑→ 0 | with high doses |
| Benzodiazepines |
| Low dose | Loss of α, increased frontal β activity | ↓ | No |
| High dose | Frontally dominant δ and θ | ↑ | |
| Ketamine |
| Moderate dose | Frontal rhythmic θ | ↑ | No |
| High dose | Polymorphic δ, some β | ↑↑ (β is low amplitude) | |
| Etomidate |
| Moderate dose | Frontal α frequency | ↑ | Yes, |
| Increasing high dose | Diffuse δ→burst suppression→silence | ↑↑→ 0 | with high doses |
| Opioids |
| Moderate dose | Diffuse θ, some δ | ↑ | No |
| High dose | δ, often synchronized | ↑↑ | |